Osmosis Jones is a 2001 live-action/animated comedy film directed by Tom Sito and Piet Kroon for the animated segments and the Farrelly brothers for the live-action segments. The film was released on August 7, 2001 by Warner Bros. Pictures.
Character Voices
- Osmosis Jones - Chris Rock
- Thrax - Laurence Fishburne
- Drix - David Hyde Pierce
- Leah - Brandy Norwood
- The Mayor - William Shatner
- Tom Colonic - Ron Howard
Kidney Rock
- Kid Rock
- Kenny Olson
- Jason Krause
- Joe C
- Stefanie Eulinberg
- Jimmie Bones
- Uncle Kracker
Additional Character Voices
- Jonathan Adams - Sewer Germ
- Carlos Alazraqui
- Keith Anthony
- Eddie Barth
- Sally Ann Brooks
- Rodger Bumpass - Nerve Network News Announcer
- Michael Carven
- Paul Christie
- Janis Dardaris
- Wendy Dillon
- Antonio Fargas
- Eddie Frierson
- Don Fullilove
- Jackie Gonneau
- Shannon Gregory
- Rif Hutton
- Richard Horvitz
- Art Kimbro
- Joyce Kurtz
- Anne Lockhart
- Sherry Lynn
- Danny Mann
- Mickie McGowan
- "Stuttering" John Melendez
- Hector Mercado
- Paul Pape
- Marilyn Pasekoff
- Chris Phillips
- Lynne Redding
- Al Rodrigo
- Herschel Sparber
- Doug Stone
- Steve Susskind
- Keri Tombazian
- Paul Tuerpe
- Robert Wisdom